OTC TPA

Generic name
Treatment

Miscellaneous

Category

Decongestants

Sub category

Without antihistamine

Preservative agents
  • Benzalkonium chloride 0.01%
Composition
  • Brimonidine tartrate 0.025%
  • Boric acid
  • Glycerin
Format

3.5 and 7.5 ml

Dosage

q6h to q8h / max qid

Covered by RAMQ?
No
Remarks
  • Not compatible with CL wear.
  • Resume lens wear 15 minutes after instillation.
  • Contraindicated in patients receiving monoamine oxidase (MAO) inhibitor therapy.
  • Do not use over 121 days after opening.
  • Works in 1 minute and lasts up to 6 to 8 hours.
  • Decrease in scotopic pupillary diameter of 0.70 to 1 mm on average, variable depending on the color of the iris (more significant for blue irises)
  • No statistically significant evidence of IOP lowering.
Age according to official indications

18 years

Age according to clinical data

5 years

References

Compendium des produits et Spécialités pharmaceutiques 2021 (CPS)
www.e-therapeutics.ca

Pediatric & Neonatal Dosage Handbook 2020, LexiComp
www.uptodate.com

DrugDex 2021, IBM MicroMedex Web applications
www.micromedexsolutions.com

Rx Vigilance Santé 2021
vigilance.ca/dosages-pediatriques-medicaments-rxvigilance


Amélie Ganivet, optométriste
Cynthia Théberge, pharmacienne