Prescription TPA

Generic name
Treatment

Glaucoma

Category

Combinations

Sub category
Preservative agents
  • Benzalkonium chloride
Composition
  • Brinzolamide 1%
  • Brimonidine tartrate 0.2%
Format

5 ml and 10 ml

Dosage

bid

Covered by RAMQ?

Yes, 10 ml

Remarks
  • Contraindicated in patients with severe renal impairment or hepatic impairment.
  • Also contraindicated in patients with hypersensitivity to sulfonamides, patients receiving monoamine oxidase (MAO) inhibitor therapy and patients on antidepressants that affect noradrenergic transmission (e.g. tricyclic antidepressants and mianserin).
  • Throw away the 10 ml bottle 125 days after first opening.
Age according to official indications

18 years

Age according to clinical data

2 years

References

Compendium des produits et Spécialités pharmaceutiques 2021 (CPS)
www.e-therapeutics.ca

Pediatric & Neonatal Dosage Handbook 2020, LexiComp
www.uptodate.com

DrugDex 2021, IBM MicroMedex Web applications
www.micromedexsolutions.com

Rx Vigilance Santé 2021
vigilance.ca/dosages-pediatriques-medicaments-rxvigilance


Amélie Ganivet, optométriste
Cynthia Théberge, pharmacienne